Free-breathing myocardial T2* mapping using GRE-EPI and MOCO for myocardial and hepatic iron overload assessment: a multi-centre study

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Free-breathing myocardial T2* mapping using GRE-EPI and MOCO for myocardial and hepatic iron overload assessment: a multi-centre study

Background T2* measurement is widely used in the assessment of patients at risk for cardiac and hepatic iron overload (1,2). The conventional breath-hold, ECG-triggered, segmented, multi-echo gradient echo sequence (BH MGRE) used for myocardial T2* quantification (3) is very sensitive to respiratory motion and may not be feasible in patients who are unable to breath-hold. To overcome this limit...

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Free-breathing myocardial T2* mapping using GRE-EPI and automatic Non-rigid motion correction

BACKGROUND Measurement of myocardial T2* is becoming widely used in the assessment of patients at risk for cardiac iron overload. The conventional breath-hold, ECG-triggered, segmented, multi-echo gradient echo (MGRE) sequence used for myocardial T2* quantification is very sensitive to respiratory motion and may not be feasible in patients who are unable to breath-hold. We propose a free-breath...

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Free-breathing multi-slice myocardial T2 mapping using slice-selective T2 magnetization preparation

Background Quantitative myocardial T2 mapping allows non-invasive assessment of myocardial inflammation/edema [1]. Current implementations commonly use a T2-prepared (T2prep) SSFP sequence to acquire different T2 weighted images at different echo times to generate the T2 maps [2,3]. However, all current techniques are designed for single slice acquisition with long rest cycles (3-6 sec) after e...

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Free breathing myocardial T2 measurements

INTRODUCTION: Quantitative measurements of Magnetic Resonance tissue parameters is a valuable tool for tissue characterisation and functional imaging. For instance, myocardial T2 quantification is used to detect early rejection of heart transplant [1]. These T2 values are usually estimated by performing several black blood FSE sequences with different Echo Times (TE), thus requiring multiple br...

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Free-breathing myocardial T2 measurements at 1.5T

Introduction Myocardial T2 mapping is a valuable tool for tissue characterization and oedema visualization. For instance, it is used to detect early rejection of heart transplant [1]. T2 values are usually estimated by performing several black blood Fast Spin Echo (FSE) sequences with different Echo Times (TE), what requires multiple breath holds. Successive apneas could lead to misregistration...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2016

ISSN: 1532-429X

DOI: 10.1186/1532-429x-18-s1-q31